Looks like the issue is the default start method on MacOS changed from fork to spawn in Python 3.8
https://docs.python.org/3/whatsnew/3.8.html#multiprocessing
Setting the start method back to fork is a quick work around e.g.
from jitcache import Cache
import time
import multiprocessing as mp
mp.set_start_method('fork')
cache = Cache()
@cache.memoize
def slow_fn(input_1, input_2, input_3=10):
print("Slow Function Called")
time.sleep(1)
return input_1 * input_2 * input_3
print(slow_fn(10, 2))